Talking about images rather than roads, it is up to you whether or not you stick to the “rules”, but it is so often said that “rules are made to be broken”, it is almost a rule in itself that you shouldn’t stick to them!
I have used the “rule” of thirds (approximately) in the first two images below and each presents to me a different atmosphere and perspective. My personal preference is for the second shot but “to each his own”. Do you have a preference?
The “thirds” rule is broken in the third shot but the focus is on (or at least my attention was drawn to) the arc of a dog’s paw prints across the beach. I hope I have managed to frame the shot successfully. The eye follows the arc of prints and is brought neatly to a stop with the change in direction of the horizontal structure on the beach and the punctuation mark of the man – who presumably owns the invisible dog! The small proportion of land and sky simply to give the scene some geographical context.